发明名称 |
BEAD INCUBATION AND WASHING ON A DROPLET ACTUATOR |
摘要 |
The present invention relates to bead incubating and washing on a droplet actuator. Methods for incubating magnetically responsive beads that are labeled with primary antibody, a sample (i.e., analyte), and secondary reporter antibodies on a magnet, on and off a magnet, and completely off a magnet are provided. Also provided are methods for washing magnetically responsive beads using shape-assisted merging of droplets. Also provided are methods for shape-mediated splitting, transporting, and dispensing of a sample droplet that contains magnetically responsive beads. The apparatuses and methods of the invention provide for rapid time to result and optimum detection of an analyte in an immunoassay. |
申请公布号 |
WO2010042637(A3) |
申请公布日期 |
2010.07.22 |
申请号 |
WO2009US59868 |
申请日期 |
2009.10.07 |
申请人 |
ADVANCED LIQUID LOGIC, INC.;SISTA, RAMAKRISHNA;SUDARSAN, ARJUN;PAMULA, VAMSEE |
发明人 |
SISTA, RAMAKRISHNA;SUDARSAN, ARJUN;PAMULA, VAMSEE |
分类号 |
G01N33/543;C12Q1/68;G01N27/00 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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