发明名称 IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
摘要 The present invention relates to compounds of Formula I wherein R1, R2, R3, R4, R6, R7 and A are as defined. Compounds of Formula I have activity inhibiting production of A&bgr;-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of Formula I.
申请公布号 US2010184737(A1) 申请公布日期 2010.07.22
申请号 US20100723511 申请日期 2010.03.12
申请人 PFIZER INC 发明人 BRODNEY MICHAEL A.;COFFMAN KAREN J.;KLEINMAN EDWARD F.;O'NEILL BRIAN T.;CHEN YUHPYNG L.
分类号 A61K31/4178;A61K31/4439;A61K31/454;A61K31/5355;A61K31/5377;A61K31/551;A61P25/00;C07D233/88;C07D401/06;C07D401/14;C07D403/06;C07D403/10;C07D413/12;C07D487/04 主分类号 A61K31/4178
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