| 发明名称 |
Method of Regulating Mammalian Target-of-Rapamycin Activity by Interaction Between Phospholipase D and Raptor |
| 摘要 |
The present invention relates to a method of regulating mammalian target-of-rapamycin (mTOR) by regulating a phospholipase D (PLD) activity that generates a complex with mTOR. Further, the present invention also relates to a method of screening inhibitors of mTOR, and a method and a composition for treating mTOR-related metabolic diseases by inhibiting mTOR. |
| 申请公布号 |
US2010184636(A1) |
申请公布日期 |
2010.07.22 |
| 申请号 |
US20070374262 |
申请日期 |
2007.08.03 |
| 申请人 |
POSTECH ACADEMY-INDUSTRY FOUNDATION |
发明人 |
RYU SUNG-HO;SUH PANN-GHILL;HA SANG-HOON;KIM DO-HYUNG;KIM IL-SHIN;KIM JUNG-HWAN;LEE MI-NAM;LEE HYUN-JU;KIM JONG-HEON;JANG SUNG-KEY;LEE TAE-HOON |
| 分类号 |
A61K38/02;A61P3/04;A61P3/10;A61P35/00;C07K2/00;C12Q1/02 |
主分类号 |
A61K38/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
