发明名称 |
METHODS OF IDENTIFYING AGENTS THAT MODULATE METHYLATION OF VEGFR1 BY SMYD3 |
摘要 |
The present invention relates to methods for determining the methyltransferase activity of a polypeptide and screening for modulators of methyltransferase activity, more particularly for modulators of the methylation of VEGFR1 by SMYD3. The invention further provides methods and pharmaceutical compositions for treating and preventing colorectal cancer, hepatocellular carcinoma, bladder cancer and/or breast cancer using a modulator so identified.
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申请公布号 |
US2010184088(A1) |
申请公布日期 |
2010.07.22 |
申请号 |
US20080664378 |
申请日期 |
2008.06.13 |
申请人 |
ONCOTHERAPY SCIENCE, INC. |
发明人 |
NAKATSURU YUSUKE |
分类号 |
G01N33/573;C07K16/40;C12Q1/48 |
主分类号 |
G01N33/573 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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