发明名称 |
FUSION MOLECULE BASED ON NOVEL TAA VARIANT |
摘要 |
This invention provides novel carbonic anhydrase (CAIX) nucleic acid and peptide sequences, as well as related methods and compositions, including anti-cancer immunogenic agent(s) (e.g. vaccines and chimeric molecules) that elicit an immune response specifically directed against cancer cells expressing a CAIX antigenic marker. The novel CAIX variant and related compositions are useful in a wide variety of treatment modalities including, but not limited to protein vaccination, DNA vaccination, and adoptive immunotherapy.
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申请公布号 |
US2010183637(A1) |
申请公布日期 |
2010.07.22 |
申请号 |
US20070520084 |
申请日期 |
2007.12.21 |
申请人 |
THE REGENTS OF TEH UNIVERSITY OF CALIFORNIA |
发明人 |
LI ZHENHUA;BELLDEGRUN ARIE S. |
分类号 |
A61K39/00;A61K31/7088;A61K35/12;A61P35/00;C07H21/00;C07K14/00;C12N5/10;C12N15/09;C12N15/74;G01N33/574 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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