| 发明名称 |
NON-PEPTIDYL, POTENT, AND SELECTIVE MU OPIOID RECEPTOR ANTAGONISTS |
| 摘要 |
Selective, non-peptide antagonists of the ma opioid receptor { MOR) and methods of their use are provided. The antagonists may be used, for example, to identify MOR agonists in competitive binding assays, and to treat conditions related to addiction in which MOR is involved, e.g. heroin, prescription drug and alcohol addiction. |
| 申请公布号 |
WO2010083384(A2) |
申请公布日期 |
2010.07.22 |
| 申请号 |
WO2010US21157 |
申请日期 |
2010.01.15 |
| 申请人 |
VIRGINIA COMMONWEALTH UNIVERSITY;ZHANG, YAN;SELLEY, DANA, E.;DEWEY, WILLIAM |
发明人 |
ZHANG, YAN;SELLEY, DANA, E.;DEWEY, WILLIAM |
| 分类号 |
C07D491/10;A61K31/4355;A61P25/32;C07D403/12;C07D405/12 |
主分类号 |
C07D491/10 |
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