发明名称 VASCULAR ENDOTHELIAL CELL-BINDING PEPTIDE
摘要 A peptide consisting of an amino acid sequence represented by any one of SEQ ID Nos. 1 to 76 of the present invention, a peptide consisting of an amino acid sequence in which one or several amino acids are substituted, deleted, inserted or added in these amino acid sequences, and having an ability to bind to, or to be taken into an activated vascular endothelial cell, or a peptide containing the above peptide as a partial sequence, and having an ability to bind to, or to be taken into an activated vascular endothelial cell is a novel peptide ligand specifically binding to a neovascular endothelial cell, and such a ligand can be effectively used for treating and diagnosing a disease accompanying vascularization such as a solid tumor.
申请公布号 US2010184695(A1) 申请公布日期 2010.07.22
申请号 US20070521981 申请日期 2007.12.21
申请人 KOYAMATSU YUICHI;MICALLEF MARK;IDA NOBUO;KOIWA MASAKAZU;KAKIZAWA YOSHINORI 发明人 KOYAMATSU YUICHI;MICALLEF MARK;IDA NOBUO;KOIWA MASAKAZU;KAKIZAWA YOSHINORI
分类号 A61K38/10;A61K38/08;A61P17/06;A61P19/02;A61P27/02;A61P35/00;C07H21/04;C07K7/06;C07K7/08 主分类号 A61K38/10
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