发明名称 |
METHOD OF TREATING CANCER USING A SURVIVIN INHIBITOR |
摘要 |
<p>Disclosed herein are methods of treating cancer by administering to a patient a small molecule inhibitor of Survivin. Also disclosed herein are methods of inhibiting Survivin dimerization in a patient by administering a compound of formula (I), (II), (III), or (IV). Methods of inducing cell cycle arrest in cancer cells, comprising G2/M stage arrest, in a patient by administering a compound of formula (I), (II), (III), or (IV) are also disclosed. Further disclosed herein are methods of inducing apoptosis in cancer cells in a patient by administering a compound of formula (I), (II), (III), or (IV).</p> |
申请公布号 |
WO2010083505(A1) |
申请公布日期 |
2010.07.22 |
申请号 |
WO2010US21365 |
申请日期 |
2010.01.19 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;BEREZOV, ALAN;WANG, QIANG;MURALI, RAMACHANDRAN;GREENE, MARK, I. |
发明人 |
BEREZOV, ALAN;WANG, QIANG;MURALI, RAMACHANDRAN;GREENE, MARK, I. |
分类号 |
A01N43/40 |
主分类号 |
A01N43/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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