发明名称 |
4,5-BIS(4-METHOXYPHENYL)IMIDAZOLE COMPOUND INDUCING DIFFERENTIATION OF MYOBLASTS OR MUSCLE FIBERS INTO NEURON CELLS, A PHARMACEUTICAL COMPOSITION INCLUDING SAID COMPOUND, A METHOD OF INDUCING NEURON CELLS DIFFERENTIATION AND A SCREENING METHOD FOR IDENTIFYING ADDITIONAL COMPOUND USEFUL FOR INDUCING NEURON CELLS DIFFERENTIATION |
摘要 |
The present invention relates to 4,5-bis(4-methoxyphenyl)imidazole compound inducing differentiation of myoblasts or muscle fibers into neuron cells, a pharmaceutical composition including said compound, a method of inducing neuron cells differentiation and a screening method for identifying additional compound useful for inducing neuron cells differentiation. More specifically, it relates to 2-{2-[5-(3-chlorophenyl)]furanyl}-4,5-bis(4-methoxyphenyl)imidazole that induces differentiation of myoblasts or muscle fibers into neuron cells, all pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug thereof, and a pharmaceutical composition including said compound, a method of inducing neuron cells differentiation and a screening method for identifying additional compound useful for inducing neuron cells differentiation.
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申请公布号 |
US2010184097(A1) |
申请公布日期 |
2010.07.22 |
申请号 |
US20100749922 |
申请日期 |
2010.03.30 |
申请人 |
INDUSTRY-ACADEMIC CORPORATION FOUNDATION, YONSEI UNIVERSITY |
发明人 |
SHIN IN-JAE;LEE MYUNG-RYUL;WILLIAMS DARREN |
分类号 |
G01N33/567;C07D233/54;C12N5/071 |
主分类号 |
G01N33/567 |
代理机构 |
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主权项 |
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地址 |
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