摘要 |
The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-di]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases. |
申请人 |
INCYTE CORPORATION;ZHOU, JIACHENG;LIU, PINGLI;LIN, QIYAN;METCALF, BRIAN, W.;MELONI, DAVID;PAN, YONGCHUN;XIA, MICHAEL;LI, MEI;YUE, TAI-YUEN;RODGERS, JAMES, D.;WANG, HAISHENG |
发明人 |
ZHOU, JIACHENG;LIU, PINGLI;LIN, QIYAN;METCALF, BRIAN, W.;MELONI, DAVID;PAN, YONGCHUN;XIA, MICHAEL;LI, MEI;YUE, TAI-YUEN;RODGERS, JAMES, D.;WANG, HAISHENG |