发明名称 |
De Novo Synthesis of Conjugates |
摘要 |
The invention provides methods for the preparation of small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer obtained from a water-soluble oligomer composition. Such drugs are produced through modification of a synthetic pathway to attach the oligomer to an intermediate compound followed by completion of the synthetic path.
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申请公布号 |
US2010184989(A1) |
申请公布日期 |
2010.07.22 |
申请号 |
US20080530438 |
申请日期 |
2008.03.12 |
申请人 |
NEKTAR THERAPEUTICS |
发明人 |
RIGGS-SAUTHIER JENNIFER;DENG BO-LIANG;REN ZHONGXU;ZHANG WEN;GU XUYUAN;DUARTE FRANCO J. |
分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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