| 发明名称 |
Fusion Proteins Comprising CD4 Minimal Modules and Methods of Use Thereof |
| 摘要 |
Fusion proteins comprising CD4 minimal modules that bind to HIV Env polypeptides in a non-CD4 backbone are described. Also described are complexes of these fusion proteins with Env as well as methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided.
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| 申请公布号 |
US2010183653(A1) |
申请公布日期 |
2010.07.22 |
| 申请号 |
US20070597340 |
申请日期 |
2007.08.03 |
| 申请人 |
CHIRON CORPORATION |
发明人 |
MASIGNANI VEGA;SCARSELLI MARIA;CAPECCHI BARBARA;SHARMA VICTORIA;BARNETT SUSAN W.;SRIVASTAVA INDRESH K.;RAPPUOLI RINO |
| 分类号 |
A61K39/02;A61K39/21;C07H21/04;C07K14/155;C07K14/24;C07K16/00;C12N1/19;C12N1/21;C12N5/10;C12N15/63;C12P21/06 |
主分类号 |
A61K39/02 |
| 代理机构 |
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