| 发明名称 |
CRYSTALLINE PEPTIDE EPOXY KETONE PROTEASE INHIBITORS AND THE SYNTHESIS OF AMINO ACID KETO-EPOXIDES |
| 摘要 |
<p>The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides.</p> |
| 申请公布号 |
EP2207791(A1) |
申请公布日期 |
2010.07.21 |
| 申请号 |
EP20080834964 |
申请日期 |
2008.10.03 |
| 申请人 |
ONYX THERAPEUTICS, INC. |
发明人 |
PHIASIVONGSA, PASIT;SEHL, LOUIS, C.;FULLER, WILLIAM, DEAN;LAIDIG, GUY, J. |
| 分类号 |
A61P19/08;A61K38/06;A61P25/28;A61P31/00;A61P33/00;A61P35/00;A61P37/00;A61P37/06;C07D301/00;C07D301/03;C07D303/36;C07K5/087 |
主分类号 |
A61P19/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
