发明名称 |
3-SUBSTITUTED (3-PHENYL)-PROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF METABOLIC DISORDERS |
摘要 |
The present invention provides compounds useful, for example, for modulating insulin levels in a subject, having the general formula I: wherein Q is an optionally substituted phenyl; L is a bond or O; P is a benzene or an optionally substituted thiazole ring; and R1 has the values provided herein. The present invention also provides compositions, uses, and methods for use of the compounds, for instance, for treatment of type II diabetes.
|
申请公布号 |
CA2607848(C) |
申请公布日期 |
2010.07.20 |
申请号 |
CA20062607848 |
申请日期 |
2006.05.18 |
申请人 |
AMGEN INC. |
发明人 |
HOUZE, JONATHAN;LIU, JIWEN;MA, ZHIHUA;MEDINA, JULIO C.;SCHMITT, MICHAEL J.;SHARMA, RAJIV;SUN, YING;WANG, YINGCAI;ZHU, LIUSHENG |
分类号 |
C07D233/54;A61K31/41;A61K31/4164;A61K31/4196;A61K31/421;A61K31/427;A61P3/04;A61P3/06;A61P3/10;C07D249/08;C07D257/04;C07D263/32;C07D277/24;C07D417/12 |
主分类号 |
C07D233/54 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|