发明名称 3-SUBSTITUTED (3-PHENYL)-PROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF METABOLIC DISORDERS
摘要 The present invention provides compounds useful, for example, for modulating insulin levels in a subject, having the general formula I: wherein Q is an optionally substituted phenyl; L is a bond or O; P is a benzene or an optionally substituted thiazole ring; and R1 has the values provided herein. The present invention also provides compositions, uses, and methods for use of the compounds, for instance, for treatment of type II diabetes.
申请公布号 CA2607848(C) 申请公布日期 2010.07.20
申请号 CA20062607848 申请日期 2006.05.18
申请人 AMGEN INC. 发明人 HOUZE, JONATHAN;LIU, JIWEN;MA, ZHIHUA;MEDINA, JULIO C.;SCHMITT, MICHAEL J.;SHARMA, RAJIV;SUN, YING;WANG, YINGCAI;ZHU, LIUSHENG
分类号 C07D233/54;A61K31/41;A61K31/4164;A61K31/4196;A61K31/421;A61K31/427;A61P3/04;A61P3/06;A61P3/10;C07D249/08;C07D257/04;C07D263/32;C07D277/24;C07D417/12 主分类号 C07D233/54
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