发明名称 |
Dye-sulfenates for dual phototherapy |
摘要 |
The present invention discloses dye-sulfenate derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds of the present invention may contain either a mixture of Type 1 and Type 2 agents or a single entity that integrates both units in the same molecules. The compounds are designed to produce both Type 1 and Type 2 phototherapeutic effect at once using dual wavelength light source that will produce singlet oxygen and free radicals at the lesion of interest. |
申请公布号 |
US7758861(B2) |
申请公布日期 |
2010.07.20 |
申请号 |
US20060277057 |
申请日期 |
2006.03.21 |
申请人 |
MALLINCKRODT INC. |
发明人 |
RAJAGOPALAN RAGHAVAN;ACHILEFU SAMUEL I.;BUGAJ JOSEPH E.;DORSHOW RICHARD D. |
分类号 |
A61K41/00;C07H15/26;A61K47/48;A61K49/00;A61K49/04;A61P35/00;A61P43/00;C07C313/08;C07D209/12;C07D209/60;C07D311/82;C07D405/12;C07K7/06;C07K14/575;C09B17/00;C09B19/00;C09B23/00;C09B23/01;C09B23/08;C09B47/00;C09B57/00 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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