发明名称 Dye-sulfenates for dual phototherapy
摘要 The present invention discloses dye-sulfenate derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds of the present invention may contain either a mixture of Type 1 and Type 2 agents or a single entity that integrates both units in the same molecules. The compounds are designed to produce both Type 1 and Type 2 phototherapeutic effect at once using dual wavelength light source that will produce singlet oxygen and free radicals at the lesion of interest.
申请公布号 US7758861(B2) 申请公布日期 2010.07.20
申请号 US20060277057 申请日期 2006.03.21
申请人 MALLINCKRODT INC. 发明人 RAJAGOPALAN RAGHAVAN;ACHILEFU SAMUEL I.;BUGAJ JOSEPH E.;DORSHOW RICHARD D.
分类号 A61K41/00;C07H15/26;A61K47/48;A61K49/00;A61K49/04;A61P35/00;A61P43/00;C07C313/08;C07D209/12;C07D209/60;C07D311/82;C07D405/12;C07K7/06;C07K14/575;C09B17/00;C09B19/00;C09B23/00;C09B23/01;C09B23/08;C09B47/00;C09B57/00 主分类号 A61K41/00
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