发明名称 |
Transformed cell with enhanced sensitivity to antifungal compound and use thereof |
摘要 |
The present invention provides a transformed cell in which a polynucleotide having a nucleotide sequence encoding an amino acid sequence of an osmosensing histidine kinase having no transmembrane region is introduced in a functional form into a cell deficient in at least one hybrid-sensor kinase, a method of assaying the antifungal activity of a test substance using the transformed cell, and a method of searching an antifungal compound using the method, and the like.
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申请公布号 |
US7759084(B2) |
申请公布日期 |
2010.07.20 |
申请号 |
US20080272705 |
申请日期 |
2008.11.17 |
申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
NAKAJIMA HIROKI |
分类号 |
C12Q1/48;C07H21/04;C12N1/15;C12N1/20;C12N9/12 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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