| 摘要 |
#CMT# #/CMT# Pharmaceutical tablet comprises a mass of single powder particles, where a diffractive microstructure, which shows a recognizable bending effect in the visible spectral area, is arranged on at least a part of the surface of the tablet and the diffractive microstructure is impressed into the surface of the single powder particle. #CMT#USE : #/CMT# The invention deals with a pharmaceutical tablet with a diffractive microstructure. #CMT#ADVANTAGE : #/CMT# The tablet exhibits high mechanical stability. The tablet exhibits high resistance against elastic deformation. The security feature of the tablet cannot be: removed and retroactively transferred to the falsified products. #CMT#PHARMACEUTICALS : #/CMT# Preferred Components: The lattice microstructure exhibits a relief with an essentially triangular or sinusoidal profile. The lattice microstructure is a linear lattice or a hole-pitch lattice. The periodic length of the lattice microstructure is 300-5000 (preferably 800-2500) nm. The depth of the relief between the grid lines of the lattice microstructure is 80 (preferably 400) nm. The depth of the relief between the lattice lines of the lattice microstructure is up to 1000 nm. The depth of the relief between the lattice lines of the lattice microstructure is 0.3-0.4 period length of the lattice microstructure. The tablet is provided with a coating, which is transparent in the visible spectral region and exhibits a difference in refractive index, from the tablet material, of at least 0.2. The refractive index of the coating is higher than the refractive index of the tablet material, and the thickness of the coating is less than 1mu m. The tablet exhibits at least a recess in the surface, in which the lattice microstructure is arranged. The tablet is manufactured by direct tabletting. #CMT#ADMINISTRATION : #/CMT# Administration of the tablet is via suppositories. #CMT#EXAMPLE : #/CMT# The typical composition comprised of lactose-monohydrate (72.75 wt.%), microcrystalline cellulose (24.25 wt.%), Aerosil (RTM: Colloidal silica) (1 wt.%), magnesium stearate (1 wt.%) and sodium salicylate (1 wt.%). |
