| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a mutant gluconate dehydrogenase having a predetermined level or higher of enzymatic activity and/or heat resistance. Ž<P>SOLUTION: The mutant gluconate dehydrogenase comprises an amino acid sequence produced by deleting, substituting, adding or inserting one or several amino acids in the amino acid sequence represented by a specific sequence, has enzymatic activity that is 120% or more of that of wild-type gluconate dehydrogenase that comprises the specific amino acid sequence, and/or, after the mutant gluconate dehydrogenase is subjected to a heat treatment under predetermined conditions, has residual enzymatic activity that is 20% or more of the enzymatic activity before the heat treatment. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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