摘要 |
<p>A method for preventing and/or treating a metabolic disease, cerebrovascular disease, etc. which comprises administering to a mammal an effective amount of the compound of the formula (I) wherein all symbols have the same meanings as defined in the specification; a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. And a novel compound of the formula (I-1): wherein all symbols have the same meanings as defined in the specification; a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof has an anti-diabetic effect and a neuroprotective effect. Accordingly, the compound of the formula (I) and the compound of the formula (I-1) are useful in a method for preventing and/or treating for a metabolic disease such as diabetes, cerebrovascular disease such as stroke, etc.</p> |
申请人 |
ARRAY BIOPHARMA INC.;RODRIGUEZ, MARTHA, E.;MARESKA, DAVID, A.;HANS, JEREMY, J.;HARVEY, DARREN, M.;GRONEBERG, ROBERT, D.;O'SULLIVAN, MICHAEL |
发明人 |
RODRIGUEZ, MARTHA, E.;MARESKA, DAVID, A.;HANS, JEREMY, J.;HARVEY, DARREN, M.;GRONEBERG, ROBERT, D.;O'SULLIVAN, MICHAEL |