发明名称 |
CORONAVIRUS-ÄHNLICHE PARTIKEL ENTHALTENDE FUNKTIONELL DELETIERTE GENOME |
摘要 |
<p>The invention relates to the field of coronaviruses and diagnosis, therapeutics, and vaccines derived thereof. Methods are shown for at least in part inhibiting anti-parallel coiled coil formation of a coronavirus spike protein wherein the methods include decreasing the contact between heptad repeat regions of the protein. The invention provides a peptide including a heptad repeat region of a corona viral spike protein and/or a functional fragment and/or an equivalent thereof. The invention also provides antibodies and inhibiting compounds.</p> |
申请公布号 |
AT473274(T) |
申请公布日期 |
2010.07.15 |
申请号 |
AT20020738952T |
申请日期 |
2002.05.17 |
申请人 |
UNIVERSITEIT UTRECHT;STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN |
发明人 |
ROTTIER, PETRUS;DE HAAN, CORNELIS;HAIJEMA, BERT;BOSCH, BEREND |
分类号 |
C12N7/04;C12N15/09;A61K35/76;A61K38/00;A61K39/215;A61K39/225;A61K39/395;A61K48/00;A61K49/00;A61P1/16;A61P7/00;A61P7/04;A61P7/06;A61P11/00;A61P31/00;A61P31/12;A61P31/16;A61P31/20;A61P31/22;A61P35/02;A61P37/04;C07K14/165;C12N5/06;C12N5/16;C12N7/00;C12N15/86;C12P21/06;C12Q1/68;C12Q1/70;G01N33/569 |
主分类号 |
C12N7/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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