发明名称 |
DISPLAY VECTORS AND METHODS AND USES THEREOF |
摘要 |
<p>The present invention relates, in one aspect, to a vector comprising (a) a first polynucleotide capable of encoding a first (poly)peptide comprising at least one cysteine residue, and (b) a second polynucleotide capable of encoding a second (poly)peptide which is a cell surface anchor comprising at least one cysteine residue, wherein the vector is operable in a eukaryotic host cell to express and to cause or allow the attachment of said first (poly)peptide to said second (poly)peptide by formation of a disulfide bond between said cysteine residues comprised within said first (polypeptide and said second (poly)peptide, respectively, wherein said first (poly)peptide is exhibited at the surface of a eukaryotic host cell.</p> |
申请公布号 |
WO2010079189(A1) |
申请公布日期 |
2010.07.15 |
申请号 |
WO2010EP50092 |
申请日期 |
2010.01.07 |
申请人 |
MORPHOSYS AG;ENZELBERGER, MARKUS;THIEL, PHILIPPE;PETERS, SOLVEIG;YODER, STEPHEN SCOTT |
发明人 |
ENZELBERGER, MARKUS;THIEL, PHILIPPE;PETERS, SOLVEIG;YODER, STEPHEN SCOTT |
分类号 |
C07K16/00;C12N15/10;C40B40/02 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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