PHOSPHOPROTEIN ANALYSIS OF CARCINOMAS FOR ASSESSMENT OF DRUG SENSITIVITY

摘要

This invention relates generally to a treatment of cancer and more particularly to the identification of carcinomas that are likely to respond to an inhibitor of the ERBB family pathway in the carcinoma cells and to the treatment of patients having such carcinomas with such inhibitors. The invention includes, but is not limited to: 1) a method of determining if a carcinoma in a mammal is likely to respond to an ERBB family pathway inhibitor; 2) a method of treating the mammal with an ERBB family pathway inhibitor; 3) a method for identifying such inhibitors; and 4) a kit for use in such assay.