发明名称 |
ENGINEERED SERS SUBSTRATES EMPLOYING NANOPARTICLE CLUSTER ARRAYS WITH MULTISCALE SIGNAL ENHANCEMENT |
摘要 |
<p>Defined nanoparticle cluster arrays (NCAs) with total lateral dimensions of up to 25.4 µm by 25.4 µm have been fabricated on top of a 10 nm thin gold film using template guided self-assembly. This approach provides precise control of the structural parameters in the arrays allowing a systematic variation of the average number of nanoparticles in the clusters (n) and the edge to edge separation (?) between 1 < n < 20 and 50 nm =?=1000 nm, respectively. Investigations of the Rayleigh scattering spectra and surface enhanced Raman scattering (SERS) signal intensities as a function of n and ? reveal direct near-field coupling between the particles within individual clusters, whose strength increases with the cluster size (n) until it saturates at around n = 4. Our analysis shows that strong near-field interactions between individual clusters significantly affects the SERS signal enhancement for edge-to-edge separations ? < 200 nm. The observed dependencies of the Raman signals on n and ? indicate that NCAs support a multiscale signal enhancement which originates from simultaneous inter- and intra-cluster coupling and |E|- field enhancement. The NCAs provide strong SERS signals of bacterial cells thus enabling a rapid and reliable spectral identification of bacteria.</p> |
申请公布号 |
WO2010081088(A1) |
申请公布日期 |
2010.07.15 |
申请号 |
WO2010US20640 |
申请日期 |
2010.01.11 |
申请人 |
TRUSTEES OF BOSTON UNIVERSITY;REINHARD, BJOERN MARCUS;DAL NEGRO, LUCA |
发明人 |
REINHARD, BJOERN MARCUS;DAL NEGRO, LUCA |
分类号 |
G01J3/433;G01J3/44 |
主分类号 |
G01J3/433 |
代理机构 |
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代理人 |
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地址 |
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