NEW RECEPTOR BINDING LIGANDS, THEIR USE IN THE DETECTION OF CELLS WITH BIOLOGICAL INTEREST

摘要

The present invention relates to the use of at least two soluble receptor binding ligands derived from the soluble part of the glycoprotein of an enveloped virus that interacts with a cellular cognate receptor, said receptor binding ligand containing a part or the totality of one of the receptor binding domains (RBD) of said glycoprotein, and said soluble receptor binding ligand being liable to interact with said at least one membrane receptor of a target cell, for the identification and quantification of the expression of membrane receptors present on the surface of target cells, said identification and quantification taking place at a given time or during a given time interval, and allowing the determination of a physiological state of said target cell.