发明名称 |
COMPOUNDS FOR INHIBITING CELL PROLIFERATION |
摘要 |
Compounds of formula (I) and (II) are provided as modulators of Rb:Raf-1 interactions which are potent, selective disruptors of Rb:Raf-1 binding. Therapeutic methods of using the compounds, for example for treating or ameliorating a cell proliferation disorder such as cancer, are provided. |
申请公布号 |
WO2010025448(A3) |
申请公布日期 |
2010.07.15 |
申请号 |
WO2009US55509 |
申请日期 |
2009.08.31 |
申请人 |
UNIVERSITY OF SOUTH FLORIDA;SEBTI, SAID M.;CHELLAPPAN, SRIKUMAR;LAWRENCE, NICHOLAS JAMES |
发明人 |
SEBTI, SAID M.;CHELLAPPAN, SRIKUMAR;LAWRENCE, NICHOLAS JAMES |
分类号 |
C07C335/00;A61K31/155;A61K31/36;A61P31/00;C07D317/56 |
主分类号 |
C07C335/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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