<p>Discloses are compounds according to Formula I. Further provided are methods of reducing oxidative stress in a cell, methods of treating a disease including cancer, and methods of treating a subject with a disorder associated with oxidative stress, the methods including administering a compound according to the invention. Also disclosed are methods of potentiating a cancer cell for treatment with ionizing radiation or chemotherapeutics including contacting the cell with an effective amount of a compound according to the invention. Further discloses are pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a compound according to the invention.</p>
申请公布号
WO2010080881(A1)
申请公布日期
2010.07.15
申请号
WO2010US20328
申请日期
2010.01.07
申请人
BATINIC-HABERLE, INES;DUKE UNIVERSITY;REBOUCAS, JULIO, S.;SPASOJEVIC, IVAN
发明人
BATINIC-HABERLE, INES;REBOUCAS, JULIO, S.;SPASOJEVIC, IVAN