ANTI-CD70 ANTIKÖRPER-ARZNEIMITTELKONJUGATE UND IHRE VERWENDUNG ZUR BEHANDLUNG VON KREBS

摘要

Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions.