发明名称 CRYSTALLINE IRINOTECAN HYDROCHLORIDE AND METHODS FOR ITS PREPARATION
摘要 Disclosed is a crystalline form of irinotecan hydrochloride (I) and processes for the preparation thereof from crude irinotecan hydrochloride or another polymorphic form of irinotecan. Said crystalline form is particularly suitable for industrial use, because it is easily filtered and possesses characteristics of high stability and purity.
申请公布号 US2010179180(A1) 申请公布日期 2010.07.15
申请号 US20090615334 申请日期 2009.11.10
申请人 ANTIBIOTICOS S.P.A. 发明人 POZZI GIOVANNI;GHETTI PAOLO;BALSAMO GAETANO;NEGRI ETTORE;ALPEGIANI MARCO;BEDESCHI ANGELO;PIZZOCARO ROBERTA
分类号 A61K31/4375;A61P43/00;C07D491/22 主分类号 A61K31/4375
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