发明名称 |
POLYMER CONJUGATE OF STEROID |
摘要 |
<p>Enzymes in the body vary among different species, and also vary among individuals of the same species. Thus, it has been demanded to develop a novel steroid-containing pharmaceutical preparation which can release a drug in a manner independent of the enzymes present in the body, and which is expected to have an efficacious therapeutic effect. Disclosed is a high-molecular weight conjugate of a steroid, comprising a structure in which a carboxylic acid group of a polymer having a polyethylene glycol moiety and a succinic acid monoamide moiety having two or more succinic acid monoamide units is ester-bonded to a hydroxy group in the steroid.</p> |
申请公布号 |
EP2206502(A1) |
申请公布日期 |
2010.07.14 |
申请号 |
EP20080832868 |
申请日期 |
2008.09.26 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
KITAGAWA, MASAYUKI;MURATA, TOSHITAKA |
分类号 |
A61K31/785;A61K47/48;A61P29/00;A61P31/00;A61P35/00;A61P37/02;A61P37/08;A61P43/00 |
主分类号 |
A61K31/785 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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