发明名称 |
Defensin-antigen fusion proteins |
摘要 |
The present invention relates to a vaccine for increasing the immunogenicity of a tumor antigen thus allowing treatment of cancer, as well as a vaccine that increases the immunogenicity of a viral antigen, thus allowing treatment of viral infection, including immunodeficiency virus (HIV) infection. In particular, the present invention provides a fusion protein comprising a defensin fused to either a tumor antigen or viral antigen which is administered as either a protein or nucleic acid vaccine to elicit an immune response effective in treating cancer or effective in treating or preventing viral infection. |
申请公布号 |
US7754676(B2) |
申请公布日期 |
2010.07.13 |
申请号 |
US20010380926 |
申请日期 |
2001.09.17 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
KWAK LARRY W.;BIRAGYN ARYA |
分类号 |
C07K14/00;A61K38/00;A61P31/12;A61P35/00;C07K14/47;C12N1/21 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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