发明名称 |
METHOD OF FORECASTING OF PRIMARY ADENTIAE |
摘要 |
FIELD: medicine. ^ SUBSTANCE: to predict the primary adentiae DNA is extricate out of venous blood lymphocytes. Genotyping of polymorphisms of gene Glutathione S-transferase Ml (GSTM1) and locus 677C> T (Ala222Val) of methylenetetrahydrofolate reductase gene (MTHFR) is carried out using the method of polymerase chain reaction. At detection of gene deletions GSTM1 in combination with homozygous in mutation genotype of MTHFR*TT risk of primary adentiae is predicted. ^ EFFECT: method enables to carry out an accurate prediction of the disease through the identification of molecular genetic markers. ^ 1 tbl, 2 ex |
申请公布号 |
RU2394242(C1) |
申请公布日期 |
2010.07.10 |
申请号 |
RU20090116057 |
申请日期 |
2009.04.27 |
申请人 |
GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "BASHKIRSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET FEDERAL'NOGO AGENTSTVA PO ZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU" (GOU VPO BGMU ROSZDRAVA) |
发明人 |
CHUJKIN SERGEJ VASIL'EVICH;VIKTOROVA TAT'JANA VIKTOROVNA;CHUJKIN OLEG SERGEEVICH;AVER'JANOV SERGEJ VITAL'EVICH |
分类号 |
G01N33/48 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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