| 摘要 |
FIELD: chemistry; pharmaceutics. ^ SUBSTANCE: present invention relates to a solid pharmaceutical composition for treating malignant tumours, including malignant tumours in the larynx, thyroid gland, perspiratory glands, kidneys, prostate gland, Hodgkin's disease, non-Hodgkin's lymphoma and leucosis, containing an effective amount of the crystalline form of suberoylanilide hydroxamic acid (SAHA), obtained through a method which involves recystallisation of an unrefined SAHA preparation from a mixture of methanol and water in ratio of approximately 2:1, and a carrier. ^ EFFECT: obtaining a solid pharmaceutical composition for treating malignant tumours. ^ 9 cl, 20 tbl, 14 dwg, 7 ex |
