| 发明名称 |
PEPTIDE INTERMEDIATES USED IN THE PRODUCTION OF BIVALIRUDIN |
| 摘要 |
The present invention relates to a process for the production of bivalirudin, a 20-mer peptide of formula H-D-Phe1-Pro-Arg-Pro-Gly5-Gly-Gly-Gly-Asn-Gly10-Asp-Phe-Glu-Glu-Ile15--Pro-Glu-Glu-Tyr-Leu20-OH (I) via a convergent five-fragment synthesis, and to several peptide intermediates thereof. |
| 申请公布号 |
CA2916716(A1) |
申请公布日期 |
2010.07.08 |
| 申请号 |
CA20092916716 |
申请日期 |
2009.12.17 |
| 申请人 |
LONZA BRAINE SA |
发明人 |
SOMMEN, GEOFFROY;FORNI, LUCIANO |
| 分类号 |
C07K7/08;C07K1/06;C07K5/107;C07K7/06;C07K14/815 |
主分类号 |
C07K7/08 |
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