Determining increased blood pressure over a previous period on blood samples comprises determining increased and/or reduced occurrence of specific marker proteins or corresponding RNA protein containing blood components in peripheral blood

摘要

Determining increased blood pressure of >= 140/90 millimeters of mercury (mm Hg) over a previous period on blood samples comprises determining increased and/or reduced occurrence of specific marker proteins or corresponding RNA protein containing blood components in peripheral blood from blood samples, where the selection of specific marker proteins or corresponding RNA is based on a comparison of protein- and RNA composition of protein blood components of peripheral blood in blood samples with a protein- and RNA composition of blood components. Determining an increased blood pressure of >= 140/90 mm Hg over a previous period on blood samples comprises determining increased and/or reduced occurrence of specific marker proteins or corresponding RNA protein containing blood components in peripheral blood from blood samples, where the increased and/or reduced occurrence of specific marker proteins is defined as a modification of an intensity by a factor of at least 1.3, and the selection of specific marker proteins or corresponding RNA is based on a comparison of protein composition and RNA composition of protein blood components of the peripheral blood in blood samples, which are associated with increased blood pressure, with a protein composition and RNA composition of blood components, which are characterized for a blood pressure of less than 140/90 mm Hg. An independent claim is included for a high blood pressure determination kit based on the above method.