摘要 |
This invention concerns a process for the co-production of glucosamine polymers (chitin, chitosan or any of its derivatives) and polymers containing glucose, mannose and/or galactose, by the high cell density fermentation of the yeast Pichia pastoris in a bioreactor under aerobic conditions, preferably using glycerol byproduct from the biodiesel industry as carbon source. Pure glycerol, pure methanol, glycerol-rich or methanol rich mixtures may also be used as carbon sources. The present invention also concerns P. pastoris fermentation process duly optimized for attaining high cell densities and high cell wall chitin content, as well as polymers containing glucose, mannose and/or galactose.
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申请人 |
73100 - SETENTA E TRES MIL E CEM, LDA;CARVALHO FERNANDES DE MIRANDA REIS, MARIA D´ASCENCAO;FREITAS OLIVEIRA, RUI MANUEL;ANDRADE DE FREITAS, MARIA FILOMENA;FERREIRA CHAGAS, BARBARA;BRAGA DA CRUZ, ANA LUISA;PIO BARBOSA PEREIRA DA CUNHA, ANTONIO EDUARDO;VAZAO MANO CLEMENTE, JOAO JOSE |
发明人 |
CARVALHO FERNANDES DE MIRANDA REIS, MARIA D´ASCENCAO;FREITAS OLIVEIRA, RUI MANUEL;ANDRADE DE FREITAS, MARIA FILOMENA;FERREIRA CHAGAS, BARBARA;BRAGA DA CRUZ, ANA LUISA;PIO BARBOSA PEREIRA DA CUNHA, ANTONIO EDUARDO;VAZAO MANO CLEMENTE, JOAO JOSE |