MATERIAL COMPOSITION AND RELATED SYSTEM AND METHOD, FOR TREATING CARDIAC CONDITION

摘要

PROBLEM TO BE SOLVED: To provide a method and its system, for treating a medical condition associated with a cardiac structure.

SOLUTION: An injectable polymer agent is injected into the cardiac structure so as to form a therapeutic mechanical scaffolding within the cardiac structure itself. Specifically, an injectable scaffolding agent 315 is a fibrin glue agent and is injected into a damaged myocardium region 304 such as ischemic tissue or infarct. LV (Left Ventricule) wall dysfunction may also be treated by injecting the scaffolding agent into the LV wall. Cell therapy may be combined with the injection of fibrin glue or other injectable polymer scaffold agent. The polymeric forms of the agent may be injectable as precursor materials that polymerize as a scaffold in-situ within the cardiac structure. In other modes, polymer agents are injected in order to provide therapeutic angiogenesis or to induce deposition of cells within injected area, such as by providing the polymer with fragment E or RDG binding sites, respectively.

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