发明名称 |
PROGNOSTIC TOOLS TO PREDICT THE EFFICACY OF DRUG TREATMENT TARGETING CHROMATIN DNA OR ENZYMES ACTING ON DNA |
摘要 |
Disclosed are methods of predicting cell response to drug-based therapy using both PCR-Stop assays and real time PCR assays. Methods herein may be used for assessment of drug effect, evaluation of regimen suitability for a given patient, and/or for determination of an optimal drug dose. Also provided are isolated oligonucleotide primers such as primers capable of annealing under PCR conditions to a segment of a c-myc locus, where the primers may be used in the disclosed methods. Further disclosed are kits and systems that may be used for predicting a cell response to drug-based therapy.
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申请公布号 |
US2010173301(A1) |
申请公布日期 |
2010.07.08 |
申请号 |
US20090630022 |
申请日期 |
2009.12.03 |
申请人 |
UNIVERSITY OF MARYLAND, BALTIMORE |
发明人 |
CARRIER FRANCE;NALABOTHULA NARASIMHAROA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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