NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF

摘要

The present invention relates to a novel Thiazolidinedione derivative expressed by the following chemical formula (1) and uses thereof. More specifically, the present invention relates to a novel Thiazolidinedione derivative expressed by the following chemical formula (1) and a pharmaceutical composition comprising the same. The novel Thiazolidinedione derivative of the following chemical formula (1) according to the present invention can be effectively used for the prevention or treatment of cardiovascular disease, gastrointestinal disease and renal disease by inhibiting the activity of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) that decomposes prostaglandins, for preventing hair loss while stimulating hair growth, for osteogenic stimulation and for the treatment of burns.