A RECOMBINANT FUSION PROTEIN, THE PREPARATION METHOD AND USE THEREOF

摘要

Provided is a fusion protein comprising of a 27-amino-acid peptide derived from the NH2-terminal domain of endostatin and Kringle5 domain derived from plasminogen. The amino acid sequence of said fusion protein is the sequence as shown in SEQ ID No.2. Said fusion protein can inhibit the proliferation of endothelial cell, and further inhibit the formation of tumor neovessels.