发明名称 |
SULFATED C-GLYCOSIDE, METHOD FOR ISOLATING SAME AND METHOD FOR SYNTHESIZING SAME |
摘要 |
Provided are a sulfated C-glycoside which is a novel compound serving as a precursor of chafuroside and chafuroside analogs; a method for efficiently producing the sulfated C-glycoside; and a method for efficiently producing chafuroside and chafuroside analogs using said sulfated C-glycoside. A sulfated C-glycoside represented by general formula (A1) or (B1) [wherein R1, R2 and R3 independently represent each a hydrogen atom or an OH group] is obtained by extracting tea leaves or tea tannins with water, a lower alcohol solvent having 1 to 3 carbon atoms or a liquid mixture comprising the same. Alternatively, the sulfated C-glycoside is produced by reacting a flavone C-glycoside such as isovitexin or vitexin with a sulfate group-introducing agent to thereby sulfate the flavone C-glycoside. By heating the sulfated C-glycoside thus obtained, chafuroside and chafuroside analogs are efficiently produced.
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申请公布号 |
CA2748729(A1) |
申请公布日期 |
2010.07.08 |
申请号 |
CA20092748729 |
申请日期 |
2009.12.25 |
申请人 |
SHIZUOKA PREFECTURE PUBLIC UNIVERSITY CORPORATION |
发明人 |
ISHIDA, HITOSHI |
分类号 |
C07D407/04;A61K31/352;A61K36/00;A61P17/00;A61P29/00;A61P35/00;A61P37/08;A61P39/06;C07D493/14 |
主分类号 |
C07D407/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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