发明名称 |
Cellular Libraries of Peptide Sequences (CLiPS) and Methods of Using the Same |
摘要 |
The present invention provides compositions including peptide display scaffolds that present at least one candidate peptide and at least one detectable moiety in at least one of the N-terminal and C-terminal candidate peptide presenting domains that when expressed in a cell are accessible at a surface of the cell outermembrane. In addition, the present invention also provides kits and methods for screening a library of cells presenting the candidate peptides in peptide display scaffolds to identify a ligand for an enzyme.
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申请公布号 |
US2010173349(A1) |
申请公布日期 |
2010.07.08 |
申请号 |
US20090646323 |
申请日期 |
2009.12.23 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
DAUGHERTY PATRICK SEAN;BOULWARE KEVIN TODD |
分类号 |
C12Q1/02;C07K14/00 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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