COMPOUNDS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES OF THE CNS
摘要
<p>Inflammatory diseases in the CNS can be treated or alleviated by the administration of an oligonucleotide in an amount sufficient to reduce the influx of mononuclear cells to the central nervous system by down-regulating the expression of at least one cell surface marker. For example multiple sclerosis can be treated or at least alleviated, by the administration of an oligonucleotide in a dose effective to inhibit or reduce the influx of mononuclear and/or autoaggressive cells to the central nervous system. The oligonucleotide can be used alone, or in combination with other treatment strategies.</p>
申请公布号
WO2010053435(A3)
申请公布日期
2010.07.08
申请号
WO2009SE51247
申请日期
2009.11.04
申请人
INDEX PHARMACEUTICALS AB;BANDHOLTZ, LISA CHARLOTTA;GIELEN, ALEXANDER;ZARGARI, AREZOU;VON STEIN, OLIVER;AXELSSON, LARS-GOERAN
发明人
BANDHOLTZ, LISA CHARLOTTA;GIELEN, ALEXANDER;ZARGARI, AREZOU;VON STEIN, OLIVER;AXELSSON, LARS-GOERAN