发明名称 |
Screening method, process for purifying of non-diffusible a-beta oligomers, selective antibodies against said non-diffusible a-beta oligomers and a process for manufacturing of said antibodies |
摘要 |
Screening method, process for purifying of non-diffusible A² oligomers, selective antibodies against said non-diffusible A² oligomers and a process for manufacturing of said antibodies The present invention is relates to non-diffusible globular A²(X - 38 .. 43) oligomers ("globulomers") or derivatives thereof, methods for enriching said globulomers or derivatives, compositions comprising said globulomers or derivatives, antibodies and aptamers having specificity for said globulomers or derivatives, methods for preparing such antibodies and aptamers, uses of said globulomers or derivatives, or of said antibodies or aptamers for diagnostic, therapeutic and other purposes, and corresponding methods using said globulomers or derivatives, or said antibodies or aptamers.
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申请公布号 |
EP2204381(A1) |
申请公布日期 |
2010.07.07 |
申请号 |
EP20090180982 |
申请日期 |
2006.03.03 |
申请人 |
ABBOTT GMBH & CO. KG |
发明人 |
HILLEN, HEINZ;STRIEBINGER, ANDREAS;KELLER, PATRICK;BARGHORN, STEFAN;EBERT, ULRICH |
分类号 |
C07K14/47;A61K38/17;C07K16/18;G01N33/68 |
主分类号 |
C07K14/47 |
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地址 |
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