摘要 |
<p>The present invention describes a use of a composition comprising an antibody homolog which is an antagonist of an interaction between an alpha 4 subunit-bearing integrin and a ligand for an alpha 4 subunit-bearing integrin for the preparation of a pharmaceutical composition for the treatment of fibrosis in a subject. The fibrosis is fibrosis of an internal organ, e. g. liver, lung, kidney, heart blood vessels, or gastrointestinal tract. Besides there is described the use of the composition comprising an anti-alpha4 antibody homolog, that may be a humanized, human or chimeric antibody homolog.</p> |