发明名称 Use of a composition comprising an antibody homolog which is an antagonist of an interaction between an alpha 4 subunit-bearing integrin and a ligand for an alpha 4 subunit-bearing integrin
摘要 <p>The present invention describes a use of a composition comprising an antibody homolog which is an antagonist of an interaction between an alpha 4 subunit-bearing integrin and a ligand for an alpha 4 subunit-bearing integrin for the preparation of a pharmaceutical composition for the treatment of fibrosis in a subject. The fibrosis is fibrosis of an internal organ, e. g. liver, lung, kidney, heart blood vessels, or gastrointestinal tract. Besides there is described the use of the composition comprising an anti-alpha4 antibody homolog, that may be a humanized, human or chimeric antibody homolog.</p>
申请公布号 SK287328(B6) 申请公布日期 2010.07.07
申请号 SK20010001520 申请日期 2000.04.21
申请人 BIOGEN IDEC MA INC. 发明人 GOTWALS PHILIP;LOBB ROY R.
分类号 A61K39/395;A61P1/16;A61P9/00;A61P11/00;A61P13/12;A61P17/00;A61P17/02;A61P19/02;A61P25/00;A61P27/02;A61P29/00;A61P37/00;C07K16/28 主分类号 A61K39/395
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