Thiotropium bromide crystalline monohydrate, process of its preparation and its use for the preparation of a medicament

摘要

In the present invention, there is disclosed a crystalline monohydrate of (1{alpha}, 2{beta}, 4{beta}, 5{alpha}, 7{beta})-7-[(hydroxy-di-2-thienyl-acetyl)-oxy]-9,9-dimethyl-3-oxy-9-azoniatricyclo[3.3.1.0e2,4]nonane bromide and use thereof for the preparation of a medicament exhibiting anticholinergic activity.