发明名称 |
METHOD FOR DIAGNOSING LIVER FIBROSIS |
摘要 |
The invention concerns a method for the detection of the presence and/or the severity of a liver disease in a patient comprising measuring in an isolated sample TIMP-1 (tissue inhibitor of metalloproteinase I), ferritin, at least one additional parameter selected from the group consisting of A2M (alpha-2-macroglobulin) and PI (prothrombin index) and optionally measuring at least one additional biochemical or clinical parameter and diagnosing the presence and/or severity of a liver disease based on the presence or measured levels of these parameters. The method can be used for monitoring therapeutic treatment of liver fibrosis and staging of liver fibrosis.
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申请公布号 |
CA2575405(C) |
申请公布日期 |
2010.07.06 |
申请号 |
CA20052575405 |
申请日期 |
2005.08.12 |
申请人 |
F. HOFFMANN-LA ROCHE AG;UNIVERSITE D'ANGERS |
发明人 |
HUEDIG, HENDRIK;WIENHUES-THELEN, URSULA-HENRIKE;CALES, PAUL |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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地址 |
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