发明名称 Methods for heat-stabilizing proteins with specific binding activities
摘要 It is disclosed here that a protein with a heat-labile specific binding activity can be stabilized with a saccharide compound with regard to the binding activity. To heat-stabilize the protein, it is mixed with a saccharide compound in a liquid suspension and the suspension is then dried to produce a solid that contains the protein and the saccharide. The saccharide compounds that possess the protein heat-stabilization activity include monosaccharides, disaccharides, polysaccharides, alkylated monosaccharides, alkylated disaccharides, alkylated polysaccharides, monosaccharide alcohols and alkylated monosaccharide alcohols.
申请公布号 US7750117(B2) 申请公布日期 2010.07.06
申请号 US20040777825 申请日期 2004.02.11
申请人 WISCONSIN ALUMNI RESEARCH FOUNDATION 发明人 COOK MARK E.;YANG MINGDER;ETZEL MARK R.
分类号 C07K16/02;A61K38/14;A61K38/16;A61K39/395;C07K1/107;C07K9/00;C07K16/40 主分类号 C07K16/02
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