PREPARATION METHOD OF POLYMERIC MICELLES COMPOSITION CONTAINING A POOLY WATER-SOLUBLE DRUG

摘要

PURPOSE: A method for manufacturing drug-containing polymer micelle composition is provided to easily and massively product in a short time. CONSTITUTION: A method for manufacturing polymer micelle composition containing insoluble drug comprises: a step of dissolving insoluble drug and amphiphilic block in organic solvent; and a step of adding aqueous solution to the solution to form micelle. The drug is Taxane anti-cancer drug. The amphiphilic block copolymer is a double block copolymer of hydrophilic block and hydrophobic block.