发明名称 |
HIGH PURITY (1R,2S,4R)-(-)-2-[(2'-{N,N-DIMETHYLAMINO}-ETHOXY)]-2-[PHENYL]-1,7,7-TRI-[METHYL]-BICYCLO[2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE |
摘要 |
The invention relates to high purity (1R,2S,4R)-(-)-2- [(2'-{N,N-dimethylamino} -ethoxy)] -2-[phenyl] -1,7,7-tri-[methyl] -bicyclo[2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2 % of (1R,3S,4R)-3- [(2'-{N,N- dimethylamino} -ethyl)]-1,7,7-tri- [methyl] -bicyclo [2.2.1] heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.
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申请公布号 |
CA2369393(C) |
申请公布日期 |
2010.07.06 |
申请号 |
CA20002369393 |
申请日期 |
2000.05.10 |
申请人 |
EGIS GYOGYSZERGYAR RT. |
发明人 |
LUKACS, GYULA;SIMIG, GYULA;MEZEI, TIBOR;BUDAI, ZOLTAN;PORCS-MAKKAY, MARTA;KRASZNAI, GYORGY;NAGY, KALMAN;VERECZKEYNE DONATH, GYORGYI;SZABO, TIBOR;NEMETH, NORBERT;SZULAGYI, JANOS |
分类号 |
C07C217/12;C07C217/52;A61K31/075;A61K31/13;A61K31/135;A61P25/22;C07B53/00;C07C213/00;C07C213/02;C07C217/02 |
主分类号 |
C07C217/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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