发明名称 |
Non-nucleotide compositions and method for treating pain |
摘要 |
The present invention is directed to a method of treating pain. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a P2X receptor antagonist. The methods of the present invention are useful in reducing pain, such as traumatic pain, neuropathic pain, organ pain and/or pain associated with diseases. The P2X receptor antagonists useful for this invention are non-nucleotide compounds of general Formula I. Compounds of Formula I can be used alone to treat pain. Compounds of Formula I can also be used in conjunction with other therapeutic agents or adjunctive therapies commonly used to treat pain, thus enhancing the therapeutic effect of pain reduction.
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申请公布号 |
US7749980(B2) |
申请公布日期 |
2010.07.06 |
申请号 |
US20040576859 |
申请日期 |
2004.10.21 |
申请人 |
INSPIRE PHARMACEUTICALS, INC. |
发明人 |
PLOURDE, JR. ROBERT;SHAVER SAMMY R.;ABREO MELWYN ANTHONY;ALFARO-LOPEZ LORENZO JOSUE;FENG YANGBO;KHASANOVA TATYANA V.;HOLLADAY MARK W.;CREAN CHRISTOPHER S. |
分类号 |
A01N43/04;A61K31/52;A61K31/70 |
主分类号 |
A01N43/04 |
代理机构 |
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主权项 |
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地址 |
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